Is Clinical’s Hollywood Facialist-Loved Serums and More Are 30 Percent Off During Amazon Prime Day

Celebrity facialist Shani Darden, Shay Mitchell, Lea Michele, and January Jones all use the brand's serums to maintain a dewy look — these are the bestsellers you'll want to stock up on now.

By Jamie Ballard

Plus Icon

Jamie Ballard

More Stories by

View All

July 8, 2025 2:21am

Add us as a Google Preferred Source

iS CLINICAL Extreme Protect SPF 30 Sunscreen

Is Clinical skincare Courtesy of Amazon

If you purchase an independently reviewed product or service through a link on our website, The Hollywood Reporter may receive an affiliate commission.

Shay Mitchell, Lea Michele, January Jones and Hollywood facialist Shani Darden are all users of Is Clinical’s range of serums, and we have a feeling you’re about to join their ranks. During Amazon Prime Day through July 11, you can grab several of the skin-care brand’s Hollywood-adored products at up to 30 percent off.

Related: The Best Amazon Prime Day Beauty Deals, from Lemme Gummies to Sunday Riley Skin-Care

Is Clinical’s Active Serum (a favorite of Mitchell, Jones and celebrity stylist Brad Goreski) gently exfoliates the skin with ingredients including bilberry extract, sugarcane and white willow bark, while arbutin and mushroom extract provide a dewy, bright look to your skin. In addition to the brand’s bestselling serums, you’ll also have a chance to grab their gentle cleaners, at-home active-peel system, and innovative eye creams, all up to a generous 30 percent off. Is Clinical products hardly ever go on sale, so we’d recommend stocking up today and tomorrow while they’re discounted.

Related Stories

Blake Griffin on the set of his new late-night show 'The Stepback with Blake Griffin.'

TV

Blake Griffin Really Wants to Be John Oliver

IMDbPro Introduces Connections and Endorsements

Business

IMDb's Latest Pivot Takes a Cue From LinkedIn

If celebrity accolades aren’t enough, allow the customer reviews convince you. Verified Amazon buyers praise Is Clinical skin care as “liquid gold,” “worth every penny,” and “one of the absolute BEST skincare products.” Reviewers also suggest that a little bit goes a long way when it comes to these skincare products, so rest assured you won’t find yourself scraping the bottom of the container in two weeks.

Related: The Best Deals on NuFace Facial Toning Devices to Shop During Amazon Prime Day

Keep scrolling for the best Is Clinical deals to shop today and tomorrow, and see more from The Hollywood Reporter‘s Amazon Prime Day coverage here.

iS CLINICAL Reparative Moisture Emulsion

iS CLINICAL Reparative Moisture Emulsion

$93.50 $110 15% off

Buy at Amazon

Best Amazon Prime Day Deals 2025 On Is Clinical Serums and Skin Care

iS CLINICAL Cleansing Complex

$41.65 $49.00 15% off

Buy at Amazon

iS CLINICAL Cleansing Complex with Active Serum Bundle

iS CLINICAL Cleansing Complex with Active Serum Bundle

$100.30 $118 15% off

Buy at Amazon

Best Amazon Prime Day Deals 2025 On Is Clinical Serums and Skin Care

iS CLINICAL Cleansing Complex with Hydra-Cool Serum Bundle

$79.05 $93.00 15% off

Buy at Amazon

iS CLINICAL Pro-Heal Serum Advance+ Antioxidant-Rich Serum

iS CLINICAL Pro-Heal Serum Advance+ Antioxidant-Rich Serum

$140.25 $165 15% off

Buy at Amazon

iS CLINICAL Active Serum

iS CLINICAL Active Serum

$125.80 $148.00 15% off

Buy at Amazon

iS CLINICAL Active Peel System

Amazon

iS CLINICAL Active Peel System

$67.20 $96 30% off

Buy at Amazon

iS CLINICAL Eclipse SPF 50+ Sunscreen

iS CLINICAL Eclipse SPF 50+ Sunscreen

$44.20 $52 15% off

Buy at Amazon

iS CLINICAL Hydra-Cool Serum

iS CLINICAL Hydra-Cool Serum

$87.55 $103 15% off

Buy at Amazon

iS CLINICAL C-Eye Advance+, Brightening Under-Eye Treatment

iS CLINICAL C-Eye Advance+, Brightening Under-Eye Treatment

$49.70 $71 30% off

Buy at Amazon

iS CLINICAL Extreme Protect SPF 30 Sunscreen

iS CLINICAL Extreme Protect SPF 30 Sunscreen

$71.40 $84 15% off

Buy at Amazon

Read More About:

THR Newsletters

Sign up for THR news straight to your inbox every day

Subscribe Sign Up

More from The Hollywood Reporter

iS CLINICAL Extreme Protect SPF 30 Sunscreen

The Definitive Voice of Entertainment News

Subscribe for full access to The Hollywood Reporter

SEE MY OPTIONS Sign Up

Most Popular

James McAvoy in 'Split.'

James McAvoy Reveals Which Film Paid Him “Bonkers” Residuals

By Carly Thomas

Paul Mescal, Joseph Quinn, Barry Keoghan and Harris Dickinson as The Beatles

Sony Considering Bold Plans for 4 Beatles Movies Rollout (Exclusive)

By James Hibberd

Billy Joel in 1973 in Billy Joel: And So It Goes

Billy Joel Offers Health Update in Rare Interview as He Prepares to Sell Prized Motorcycle Collection

By Seth Abramovitch

Esther McGregor and Emilio Sakraya

‘Fourth Wing’ Series: Esther McGregor and Emilio Sakraya Cast as Violet and Xaden

By Lexy Perez

Newlyweds (l-r) Tim Daly as James, Bill O'Neill as Arvid, Al Madrigal as Dan, Ignacio Diaz-Silverio as Lolo, Tea Leoni as Jeanie, Emma Meisel as Poppy

Gail Lerner Fired From Her Own NBC Comedy ‘Newlyweds’

By Tony Maglio

Michael Che

‘SNL’ Star Michael Che Reacts to Shane Gillis’ Controversial Monologue: “That’s Comedy”

By Carly Thomas

IMDbPro Introduces Connections and Endorsements

IMDb’s Latest Pivot Takes a Cue From LinkedIn

By Alex Weprin

Must Reads

Olivia Rodrigo was photographed Aug. 21 at The Ebell of Los Angeles.

Olivia Rodrigo: The Queen of Sad Finds Her Happy Place

By Ethan Millman

Jason Sudeikis is a fixture of CeLIBrity row, the group of famous New York Liberty fans who go to see Breanna Stewart dominate the opposition. They were photographed Sept. 16 at Splashlight Studios in New York.

‘Ted Lasso’ Star Jason Sudeikis Goes One-on-One With WNBA Great Breanna Stewart (Watch)

By Julian Sancton

Bachelor Clayton Echard Love Trapped

‘Love Trapped,’ Fake Twins and the Paternity Scandal That Outcrazied ‘The Bachelor’

By Jackie Strause